APACT 25 Programme

Please note that this programme is subject to change - Last updated 24/4/25.

 


08:30 - 09:30

Registration


09:30 - 09:40

Welcome and opening of the conference


09:40 - 10:20

Keynote 1 - The metrology mindset in a digital age: quantifying confidence in advanced analytics


10:20 - 11:00

Keynote 2 - Chemometrics as a basic skill for chemists - Why is it not happening?


11:00 - 11:25

Parallel Sessions - Developments in Process Analysis

Leverage the lessons learned during development to optimize measure systems for trending and control

Parallel Sessions - Chemometrics and Advanced Data Analysis

Chemometrics versus machine learning


11:25 - 11:50

Parallel Sessions - Developments in Process Analysis

Bubbles, noise, and data: Smart techniques for detecting air entrainment

Parallel Sessions - Chemometrics and Advanced Data Analysis

Enhancing bilayer OSD manufacturing with AI/ML-driven process monitoring


11:50 - 13:00

Lunch


13:00 - 14:30

Flash Poster Presentations


14:30 - 15:00

Posters (presenters attending), exhibition and tea/coffee


15:00 - 15:25

Parallel Sessions - Developments in Process Analysis

Investigation of the feasibility and challenges of simultaneous specific quantitative analysis of a broad range of amino acids in solution with an eye toward In-line monitoring and control

Parallel Sessions - Chemometrics and Advanced Data Analysis

Advancing lean chemometrics: Iterative Optimization Technology as a process analytical technology tool for reducing calibration burden


15:25 - 15:50

Parallel Sessions - Developments in Process Analysis

Raman spectroscopy of dispersions withscattered light measurements to correct forlosses due to light refraction

Parallel Sessions - Chemometrics and Advanced Data Analysis

From complexity to clarity: Interpretableensemble strategies in semi-AutoML


15:50 - 16:15

Parallel Sessions - Developments in Process Analysis

Computer vision approach for kinetic analysisof lab- and process-scale mixing phenomenaand toward verifying CFD models

Parallel Sessions - Chemometrics and Advanced Data Analysis

A physics-based data simulation andaugmentation method for enhancingcalibration model development on a visible spectrometer


16:15 - 17:30

Exhibitor Showcase session 1 (inc. refreshments)


17:30 - 18:30

Free time


18:30 - 20:00

Dinner


20:00

Whisky tasting by William Grant & Sons


09:00 - 09:40

Keynote 3: Options for process analytical technology in continuous wet granulation manufacturing


09:40 - 10:20

Keynote 4: Thinking in higher dimensions and modes: Addressing multivariate multimodal data within framework of partial least-squares


10:20 - 10:50

Tea/coffee and exhibition and posters


10.50 - 11.15

Parallel Sessions - Pharma PAT

The speed and sustainability of transmission Raman spectroscopy for real-time release testing

Parallel Sessions - Process Optimisation & Control

Driving towards sustainable manufacturing with advanced process control and optimisation


11:15 - 11:40

Parallel Sessions - Pharma PAT

Optimising PAT for continuous direct compression using the feed frame simulator

Parallel Sessions - Process Optimisation & Control

Development of a self-optimization platform for enhanced process control in continuous flow systems


11:40 - 12:05

Parallel Sessions - Pharma PAT

Spectroscopy shootout: A comparative analysis of spectroscopic techniques for oral solid dosage forms

Parallel Sessions - Process Optimisation & Control

Real time optimization and control of processes by combining online spectroscopy monitoring, chemometrics and artificial intelligence algorithms


12:05 - 13:00

Lunch


13:00 - 14:00

Exhibition and posters


14:00 - 14:25

Parallel Sessions - Bio-process Monitoring

Implementation of novel spectroscopic and chromatographic PAT within a commercial continuous Biologics manufacturing process. Andy Kavanagh, MSD BioNX

Parallel Sessions - Process Modelling & Control

Hybrid modelling for reaction network simulation in syngas methanol production


14:25 - 14:50

Parallel Sessions - Bio-process Monitoring

Enhancing biopharmaceutical purification: Realtime column regeneration monitoring with ATEEM. Eric Teboul, HORIBA

Parallel Sessions - Process Modelling & Control

Can we develop data-driven models to guide lipid nanoparticle design?


14:50 - 15:15

Parallel Sessions - Bio-process Monitoring

Performance of cross-clone Raman calibration models in CHO cultivations. Izabella Surowiec, Sartorius Digital Solutions

Parallel Sessions - Process Modelling & Control

Applying neuroevolution and adaptive neural networks to control challenges in the process industries


15:15 - 15:45

Tea/coffee and exhibition and posters


15:45 - 16:10

Parallel Sessions - Bio-process Monitoring

Advanced real-time monitoring of nanoparticle size in bioprocessing: Applications in upstream and downstream processes

Parallel Sessions - Pharma PAT

Enhancing pharmaceutical process development and manufacturing through integration of process modelling and process analytical technology


16:10 - 16:35

Parallel Sessions - Bio-process Monitoring

Using process Raman spectroscopy as aprocess analytical technology tool for upstream processing – continuous perfusionruns, and downstream processing

Parallel Sessions - Pharma PAT

At-line real-time release testing on the absence of drug crystallinity by terahertz process analytical technology


16:35 - 17:00

Parallel Sessions - Bio-process Monitoring

Exploring standard-based and standard-free methods using ATR-FTIR technique to predict lignin’s molecular weight, ß-O-4 content and glass transition temperature

Parallel Sessions - Pharma PAT

Spatially offset Raman spectroscopy for drying monitoring in an agitated filter-dryer


17:00 - 18:00

Exhibitors' showcase session 2 (inc. refreshments)


18:00 - 19:30

Free time


19:30

Conference Dinner


09:00 - 09:40

Keynote 5: On the path to fair autonomous high throughput bioprocess development


09:40 - 10:20

Keynote 6: Digitalization challenges in food manufacturing: Application of PAT and APC in a traditional industry


10:20 - 11:00

Tea/coffee and exhibition and posters


11:00 - 11:25

Parallel Sessions - Developments in Process Analysis

Advances in fibre optic probes for in-line process control in harsh conditions

Parallel Sessions - Bio-process Modelling

Integrating AI-driven hybrid modelling and transfer learning for predicting bioprocess upscaling operations


11:25 - 11:50

Parallel Sessions - Developments in Process Analysis

Combination of an in-line ultrasonic trap and a Raman probe for the monitoring of crystallization

Parallel Sessions - Bio-process Modelling

Development of a novel mechanistic model for describing the growth and infection/transfection of HEK cells


11:50 - 12:15

Parallel Sessions - Developments in Process Analysis

Gas bottle quality monitoring with Raman spectroscopy

Parallel Sessions - Bio-process Modelling

Towards accurate prediction of cell culture dynamics in bioreactor digital twins


12:15 - 12:30

Poster prize presentation


12:30 - 12:45

Closing remarks


12:45 - 14:00

Lunch & departure