APACT 25 Programme

Please note that this programme is subject to change - Last updated 24/4/25.

 

Download APACT 2025 conference Programme (PDF)

08:30 - 09:30

Registration

09:30 - 09:40

Welcome and opening of the conference

09:40 - 10:20

Keynote 1

Keynote 1: The metrology mindset in a digital age: quantifying confidence in advanced analytics

Louise Wright is the Head of Digital Metrology and the Head of Science for Data Science at NPL. Different areas of metrology can benefit from digitalisation in different ways, and Louise’s work involves identifying activities and processes common to multiple areas, collaborating to develop appropriate solutions, and enabling knowledge to be shared across those areas to accelerate development and external uptake. She currently chairs the EURAMET TC-IM working group on Metrology for Digitalisation and the CIPM Task Group on Building Safe and Trustworthy AI.

10:20 - 11:00

Keynote 2

Keynote 2: Chemometrics as a basic skill for chemists - Why is it not happening?

A chemist and spectroscopist by background, Thomas has been working for Syngenta for almost 10 years. Throughout his career he has worked on building PAT capabilities, being it measurement concepts, data analysis techniques or process controls. In his current role, he is leading the global PAT activities in AI development and manufacturing. Through the mentoring of scientists as well as numerous internal and external talks and publications he constantly emphasizes the importance of PAT and how it can help to achieve the strategic goals of an organization.

11:00 - 11:25

Parallel Sessions - Developments in Process Analysis

Leverage the lessons learned during development to optimize measure systems for trending and control

Martin Warman, Martin Warman Consultancy

Parallel Sessions - Chemometrics and Advanced Data Analysis

Chemometrics versus machine learning

Brian Rohrback, Infometrix, Inc.

11:25 - 11:50

Parallel Sessions - Developments in Process Analysis

Bubbles, noise, and data: Smart techniques for detecting air entrainment

Ben Watson, Johnson Matthey

Parallel Sessions - Chemometrics and Advanced Data Analysis

Enhancing bilayer OSD manufacturing with AI/ML-driven process monitoring

Juan Rosas, Organon

11:50 - 13:00

Lunch

13:00 - 14:30

Flash Poster Presentations

14:30 - 15:00

Posters (presenters attending), exhibition and tea/coffee

15:00 - 15:25

Parallel Sessions - Developments in Process Analysis

Investigation of the feasibility and challenges of simultaneous specific quantitative analysis of a broad range of amino acids in solution with an eye toward In-line monitoring and control

Mark Kemper, Tornado Spectral Systems, a Bruker Company

Parallel Sessions - Chemometrics and Advanced Data Analysis

Advancing lean chemometrics: Iterative Optimization Technology as a process analytical technology tool for reducing calibration burden

Jonique Samuels, Optimal Industrial Technologies

15:25 - 15:50

Parallel Sessions - Developments in Process Analysis

Raman spectroscopy of dispersions withscattered light measurements to correct forlosses due to light refraction

Erik Spoor, Technical University of Applied Sciences Mannheim

Parallel Sessions - Chemometrics and Advanced Data Analysis

From complexity to clarity: Interpretableensemble strategies in semi-AutoML

Manny Palacios, Eigenvector Research Inc

15:50 - 16:15

Parallel Sessions - Developments in Process Analysis

Computer vision approach for kinetic analysisof lab- and process-scale mixing phenomenaand toward verifying CFD models

Calum Fyfe, University of Strathclyde

Parallel Sessions - Chemometrics and Advanced Data Analysis

A physics-based data simulation andaugmentation method for enhancingcalibration model development on a visible spectrometer

Simon Pinault, INDATECH -Chauvin Arnoux.

16:15 - 17:30

Exhibitor Showcase session 1 (inc. refreshments)

17:30 - 18:30

Free time

18:30 - 20:00

Dinner

20:00

Whisky tasting by William Grant & Sons

09:00 - 09:40

Keynote 3: Options for process analytical technology in continuous wet granulation manufacturing

David is a team leader and senior principal scientist at Pfizer where he has worked since August 2012. He has a background in PAT and analytical chemistry and completed his PhD from the University of Strathclyde as part of the CPACT group under the supervision of Prof. Alison Nordon. David is based in Groton, CT, USA and currently leads PAT development activities in the small molecule drug product analytical R&D group.

09:40 - 10:20

Keynote 4: Thinking in higher dimensions and modes: Addressing multivariate multimodal data within framework of partial least-squares

Puneet Mishra researches sensing technology and automation at Wageningen University and Research. He develop new AI methods for processing point spectral data as well as spectral images. He is developer of all-in-one spectral imaging setup and also Swiss knife chemometric algorithms. He has more than 100 articles in peer-reviewed scientific journals on topic of spectroscopy and chemometrics.

10:20 - 10:50

Tea/coffee and exhibition and posters

10.50 - 11.15

Parallel Sessions - Pharma PAT

The speed and sustainability of transmission Raman spectroscopy for real-time release testing

Nathan Cumberbatch, AstraZeneca

Parallel Sessions - Process Optimisation & Control

Driving towards sustainable manufacturing with advanced process control and optimisation

John Mack, Applied Materials

11:15 - 11:40

Parallel Sessions - Pharma PAT

Optimising PAT for continuous direct compression using the feed frame simulator

Eleonora De Giorgi University of Birmingham/AstraZeneca

Parallel Sessions - Process Optimisation & Control

Development of a self-optimization platform for enhanced process control in continuous flow systems

Gonzalo Araya Vargas, FraunhoferInstitut für Chemische Technologie

11:40 - 12:05

Parallel Sessions - Pharma PAT

Spectroscopy shootout: A comparative analysis of spectroscopic techniques for oral solid dosage forms

Jeppe Hagedorn, Novo Nordisk A/S

Parallel Sessions - Process Optimisation & Control

Real time optimization and control of processes by combining online spectroscopy monitoring, chemometrics and artificial intelligence algorithms

Manis Gheghiani, Axel'One

12:05 - 13:00

Lunch

13:00 - 14:00

Exhibition and posters

14:00 - 14:25

Parallel Sessions - Bio-process Monitoring

Implementation of novel spectroscopic and chromatographic PAT within a commercial continuous Biologics manufacturing process.

Andy Kavanagh, MSD BioNX

Parallel Sessions - Process Modelling & Control

Hybrid modelling for reaction network simulation in syngas methanol production

Harry Kay, University of Manchester

14:25 - 14:50

Parallel Sessions - Bio-process Monitoring

Enhancing biopharmaceutical purification: Realtime column regeneration monitoring with ATEEM.

Eric Teboul, HORIBA

Parallel Sessions - Process Modelling & Control

Can we develop data-driven models to guide lipid nanoparticle design?

Nima Hojat, CPI

14:50 - 15:15

Parallel Sessions - Bio-process Monitoring

Performance of cross-clone Raman calibration models in CHO cultivations.

Izabella Surowiec, Sartorius Digital Solutions

Parallel Sessions - Process Modelling & Control

Applying neuroevolution and adaptive neural networks to control challenges in the process industries

Matthew Carr, Luffy AI

15:15 - 15:45

Tea/coffee and exhibition and posters

15:45 - 16:10

Parallel Sessions - Bio-process Monitoring

Advanced real-time monitoring of nanoparticle size in bioprocessing: Applications in upstream and downstream processes

Albert Grau-Carbonell, InProcess-LSP

Parallel Sessions - Pharma PAT

Enhancing pharmaceutical process development and manufacturing through integration of process modelling and process analytical technology

Florian Zehentbauer, AstraZeneca

16:10 - 16:35

Parallel Sessions - Bio-process Monitoring

Using process Raman spectroscopy as aprocess analytical technology tool for upstream processing – continuous perfusionruns, and downstream processing

Lin Chen, ThermoFisher Scientific

Parallel Sessions - Pharma PAT

At-line real-time release testing on the absence of drug crystallinity by terahertz process analytical technology

Chi Ki Leung, University of Cambridge

16:35 - 17:00

Parallel Sessions - Bio-process Monitoring

Exploring standard-based and standard-free methods using ATR-FTIR technique to predict lignin’s molecular weight, ß-O-4 content and glass transition temperature

Abdoulah Ly, University College Dublin

Parallel Sessions - Pharma PAT

Spatially offset Raman spectroscopy for drying monitoring in an agitated filter-dryer

Samuel Santos, University of Strathclyde

17:00 - 18:00

Exhibitors' showcase session 2 (inc. refreshments)

18:00 - 19:30

Free time

19:30

Conference Dinner

09:00 - 09:40

Keynote 5: On the path to fair autonomous high throughput bioprocess development

Dr. Nicolas Cruz is the head of the KIWI-biolab within the Chair of Bioprocess Engineering at TU-Berlin. He holds a Bachelor's degree in Chemical Engineering and earned his Ph.D. specializing in Model-Based Optimization of Bioprocesses from TU Berlin. Dr. Cruz's international experience includes among others research stays at Texas A&M (in the Process Control Laboratory, Prof. Kravaris) and ETH Zurich (Morbidelli Group, focusing on biochemical engineering). The research of Dr. Nicolas Cruz focuses on the intersection of the fields of bioprocess digitalization, model-based tools for biotechnology and biopharma, High Throughput Bioprocess Development, and autonomous (self-driving) biolabs. His work is dedicated to advancing innovative solutions that address contemporary challenges for a sustainable society.

09:40 - 10:20

Keynote 6: Digitalization challenges in food manufacturing: Application of PAT and APC in a traditional industry

Caroline Welch: Having worked in Analytical R&D for Mondelez International for 10 years, Caroline has shifted her focus from the lab to Process Analytical Technology and its applications across the different snack industries encompassed by Mondelez, whether it be chocolate, biscuits or cream cheese. Working on the end-to-end implementation of PAT from technology development through to deployment, Caroline encompasses the technical - understanding the technology landscape and development of suitable technologies to integrate with process and quality systems; and the practical application - including navigating the digital and cultural readiness of manufacturing sites. Gareth Coffin: A chemical and process engineer by background, Gareth has been working in R&D roles for the food industry for almost 9 years. In everything from new technology discovery and development, to understanding rheological properties, process optimisation, productivity and formulation engineering. Most recently, Gareth has been focussing on developing Advanced Process Control technology for the Chocolate Category in Mondelez: applying emerging control technologies and PAT tools retroactively to common chocolate processes; working with fellow process developers and scientists to ensure their technologies launch with an APC solution; and scoping new inline techniques and process control technology to improve Mondelez’s capability.

10:20 - 11:00

Tea/coffee and exhibition and posters

11:00 - 11:25

Parallel Sessions - Developments in Process Analysis

Advances in fibre optic probes for in-line process control in harsh conditions

Alexander Novikov, art photonics GmbH

Parallel Sessions - Bio-process Modelling

Integrating AI-driven hybrid modelling and transfer learning for predicting bioprocess upscaling operations

Harvey Al-Ramadhan, The University of Manchester

11:25 - 11:50

Parallel Sessions - Developments in Process Analysis

Combination of an in-line ultrasonic trap and a Raman probe for the monitoring of crystallization

Christoph Gasser, usePAT

Parallel Sessions - Bio-process Modelling

Development of a novel mechanistic model for describing the growth and infection/transfection of HEK cells

Kim Kuchemuller, Sartorius

11:50 - 12:15

Parallel Sessions - Developments in Process Analysis

Gas bottle quality monitoring with Raman spectroscopy

Jessica Gabb, ISInstruments

Parallel Sessions - Bio-process Modelling

Towards accurate prediction of cell culture dynamics in bioreactor digital twins

Sarah Fadda, Siemens Industry Software Ltd.

12:15 - 12:30

Poster prize presentation

12:30 - 12:45

Closing remarks

12:45 - 14:00

Lunch & departure